FAB Research
Sermorelin + GHRP-6 — research use only
Analysis
HPLC / LC-MS
Delivery
Cold-chain
Traceability
COA per batch

Sermorelin + GHRP-6

10 mg / pen

The most classical GH axis pairing — GHRH analogue with ghrelin receptor compound — research pen

Batch reference
FR-SG6-2507
Retest date
July 2028

1 box · 10 mg per pen

$139
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Packs
1
Ships in 24hDiscreet packaging

Sermorelin + GHRP-6 is a dual-peptide research formulation combining a GHRH-receptor agonist with a ghrelin-receptor agonist. Sermorelin (5mg) activates GHRH receptors on pituitary somatotrophs via cAMP. GHRP-6 (5mg) activates GHS-R1a through G-protein and calcium signalling. Together they provide a model for investigating complementary endocrine pathways with documented synergistic growth hormone responses. GHRP-6 additionally contributes appetite-related hypothalamic signalling. Each component is assayed independently on the Certificate of Analysis. FAB Research supplies this blend as a 10mg pre-filled metered research pen.

Blend composition
  • Sermorelin (5 mg)
  • GHRP-6 (5 mg)

Each component is assayed separately on the Certificate of Analysis.

Sermorelin and GHRP-6 act through distinct receptor systems. GHRH receptor activation involves Gs protein, cAMP elevation and calcium-dependent growth hormone release, modulated by somatostatin tone. GHS-R1a activation involves phospholipase C and intracellular calcium mobilisation. The two pathways converge on pituitary somatotrophs, producing synergistic release well-documented in combination pharmacology literature. GHRP-6 additionally activates hypothalamic ghrelin circuits and has been investigated for cytoprotective effects in cardiac and gastric models independent of growth hormone release.

A historically important pairing with strong individual compound literature. Combination pharmacology studies documented synergistic growth hormone release greater than either compound alone. The selectivity profile differs from Sermorelin + Ipamorelin: GHRP-6 produces more pronounced cortisol and prolactin responses, making this combination relevant to studies where the full endocrine consequences of ghrelin receptor activation are being investigated. Note: listed by anti-doping authorities.

  • 2.5 mg per application (1.25 mg Sermorelin + 1.25 mg GHRP-6 per dose)
  • 4 doses per pen (10 mg total)
  • Dual-pathway combination: GHRH-R (Sermorelin) + GHS-R1a (GHRP-6) co-stimulation
  • Each component independently assayed on the Certificate of Analysis

Storage: Store refrigerated at 2–8 °C in the original sealed box. Do not freeze. Protect from light.

  • For in-vitro laboratory and preclinical research only — not for human or animal administration
  • GHRP-6 component is listed by WADA — detection is established
  • Dual-pathway GH secretagogue design: synergistic release greater than either component individually — well documented in combination pharmacology literature
  • GHRP-6 appetite stimulation, cortisol and prolactin elevation will be present in this combination — account for in study designs involving food intake, HPA axis or prolactin endpoints

  • Combined effects from both components
  • Pronounced appetite / hunger stimulation (GHRP-6 component — hypothalamic GHS-R1a mechanism)
  • Flushing, headache (both components contribute)
  • Transient water retention
  • Transient cortisol and prolactin elevation (GHRP-6 component — intermediate level)
  • Injection site reactions
  • Anti-doping listed (GHRP-6 component): detection established

Effects listed are observations from published research literature and are not predictions for any specific use. All FAB Research products are for in-vitro laboratory research — not for human or animal administration.

In-vitro research applications

  • Complementary GH receptor pathways
  • GHRH + ghrelin synergy
  • Appetite & hypothalamic research
  • Endocrine selectivity comparison

Research applications are provided for informational context only and do not constitute a recommendation for any use.

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